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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCL1 All Species: 22.73
Human Site: T139 Identified Species: 38.46
UniProt: Q15111 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15111 NP_006217.3 1095 122728 T139 N R F F T L D T D L Q A L R W
Chimpanzee Pan troglodytes XP_001169560 1095 122728 T139 N R F F T L D T D L Q A L R W
Rhesus Macaque Macaca mulatta XP_001089483 1095 122754 T139 N R F F T L D T D L Q A L R W
Dog Lupus familis XP_536020 1096 122535 T140 N R F F T L D T D L Q A L R W
Cat Felis silvestris
Mouse Mus musculus Q3USB7 1096 122654 T140 N R F F T L D T D L Q A L R W
Rat Rattus norvegicus Q62688 1096 122754 T140 N R F F T L D T D L Q A L R W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507313 1051 118878 I112 S E K A K I D I K S I K E V R
Chicken Gallus gallus Q2VRL0 637 72514
Frog Xenopus laevis Q32NH8 758 87399
Zebra Danio Brachydanio rerio A5D6R3 784 89362
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 H119 Y I N I T Y H H V I C P D A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_741067 1068 120024 P113 W T P T N K K P H K A R I A I
Sea Urchin Strong. purpuratus XP_001178766 684 77475
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32383 869 100529
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 98.7 96.4 N.A. 94.3 94.1 N.A. 62.9 21.7 24.7 27.9 N.A. 20 N.A. 39 35.8
Protein Similarity: 100 100 99.2 98.5 N.A. 96.6 96.6 N.A. 77.1 34.8 40.4 42.3 N.A. 40.2 N.A. 59.4 48.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 0 0 0 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 0 0 0 N.A. 13.3 N.A. 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 8 43 0 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 50 0 43 0 0 0 8 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 43 43 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 8 8 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 8 0 8 0 8 8 0 8 0 8 % I
% Lys: 0 0 8 0 8 8 8 0 8 8 0 8 0 0 0 % K
% Leu: 0 0 0 0 0 43 0 0 0 43 0 0 43 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 43 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 8 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % Q
% Arg: 0 43 0 0 0 0 0 0 0 0 0 8 0 43 8 % R
% Ser: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % S
% Thr: 0 8 0 8 50 0 0 43 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 43 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _